Featured publications
Longitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infants
April 21, 2022
Kaelin EA, Rodriguez C, Hall-Moore C, Hoffmann JA, Linneman LA, Ndao IM, Warner BB, Tarr PI, Holtz LR, Lim ES. Longitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infants. Nat Microbiol. 2022 Apr 21. doi: 10.1038/s41564-022-01096-x. Epub ahead of print. PMID: 35449461.
Growth velocity in children with Environmental Enteric Dysfunction is associated with specific bacterial and viral taxa of the gastrointestinal tract in Malawian children
June 23, 2020
Desai C, Handley SA, Rodgers R, Rodriguez C, Ordiz MI, Manary MJ, Holtz LR. Growth velocity in children with Environmental Enteric Dysfunction is associated with specific bacterial and viral taxa of the gastrointestinal tract in Malawian children. PLoS Negl Trop Dis. 2020 Jun 23;14(6):e0008387. doi: 10.1371/journal.pntd.0008387. PMID: 32574158; PMCID: PMC7310680.
Discordant transmission of bacteria and viruses from mothers to babies at birth
December 10, 2019
Maqsood R, Rodgers R, Rodriguez C, Handley SA, Ndao IM, Tarr PI, Warner BB, Lim ES, Holtz LR. Discordant transmission of bacteria and viruses from mothers to babies at birth. Microbiome. 2019 Dec 10;7(1):156. doi: 10.1186/s40168-019-0766-7. PMID: 31823811; PMCID: PMC6902606.
Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community
May 11, 2018
Lim ES, Rodriguez C, Holtz LR. Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community. Microbiome. 2018 May 11;6(1):87. doi: 10.1186/s40168-018-0475-7. Erratum in: Microbiome. 2019 Feb 12;7(1):22. PMID: 29751830; PMCID: PMC5946436.
Early life dynamics of the human gut virome and bacterial microbiome in infants
October 1, 2015
Lim ES, Zhou Y, Zhao G, Bauer IK, Droit L, Ndao IM, Warner BB, Tarr PI, Wang D, Holtz LR. Early life dynamics of the human gut virome and bacterial microbiome in infants. Nat Med. 2015 Oct;21(10):1228-34. doi: 10.1038/nm.3950. Epub 2015 Sep 14. PMID: 26366711; PMCID: PMC4710368.
Recent publications
- Relationship between exclusive breastfeeding, pet ownership, and infant healthcare utilizationTal, R. M., Walsh, L. M., Boyle, M. G., Hunter, E. R., Martin-Giacalone, M. R., Liao, S. M., Fritz, S. A. & Holtz, L. R., Aug 2024, In: Pediatric research. 96, 3, p. 543-546 4 p.Research output: Contribution to journal › Letter › peer-review
- Noninvasive Markers of Inflammation and Protein Loss Augment Diagnosis of Pediatric Celiac DiseaseSutton, K. A., He, M., Ma, C., Liu, T. C., Faubion, W. A., Hoffmann, J., Linneman, L., Rodriguez, C. & Holtz, L. R., May 1 2024, In: Clinical and Translational Gastroenterology. 15, 5, e00695.Research output: Contribution to journal › Article › peer-review
- Deploying Lactulose as a Prebiotic to Reduce Complications of Chronic Liver DiseaseHoltz, L. R. & DeBosch, B. J., Mar 2024, In: Gastroenterology. 166, 3, p. 534-535 2 p.Research output: Contribution to journal › Comment/debate
- Quantification of Enteric Dysfunction in Cystic Fibrosis: Inter- and Intraindividual VariabilityDuckworth, L. A., Sutton, K. A., Shaikh, N., Wang, J., Hall-Moore, C., Holtz, L. R., Tarr, P. I. & Rubenstein, R. C., Feb 2024, In: Journal of Pediatrics. 265, 113800.Research output: Contribution to journal › Article › peer-review
- First-in-Human Assessment of Gut Permeability in Crohn's Disease Patients Using Fluorophore TechnologyHoltz, L. R., Nix, B. D., Akuse, S. E., Hall-Moore, C., Newberry, R. D., Ciorba, M. A., Deepak, P., Zulfiqar, M., Shieh, J. J., Johnson, J. R., Riley, I. R. & Dorshow, R. B., Jan 2024, In: Gastro Hep Advances. 3, 4, p. 491-497 7 p.Research output: Contribution to journal › Article › peer-review
- Fighting the Wrong Enemy: Antibacteriophage Immunity in Phage TherapyMolleston, J. M. & Holtz, L. R., Feb 1 2023, In: Journal of Infectious Diseases. 227, 3, p. 309-310 2 p.Research output: Contribution to journal › Comment/debate
- Gut virome in early life: origins and implicationsKennedy, E. A. & Holtz, L. R., Aug 2022, In: Current Opinion in Virology. 55, 101233.Research output: Contribution to journal › Review article › peer-review
- Longitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infantsKaelin, E. A., Rodriguez, C., Hall-Moore, C., Hoffmann, J. A., Linneman, L. A., Ndao, I. M., Warner, B. B., Tarr, P. I., Holtz, L. R. & Lim, E. S., May 2022, In: Nature microbiology. 7, 5, p. 653-662 10 p.Research output: Contribution to journal › Article › peer-review
- Rhamnose Is Superior to Mannitol as a Monosaccharide in the Dual Sugar Absorption Test: A Prospective Randomized Study in Children With Treatment-Naïve Celiac DiseaseHoltz, L. R., Hoffmann, J., Linneman, L., He, M., Smyrk, T. C., Liu, T. C., Shaikh, N., Rodriguez, C., Dyer, R. B., Singh, R. J. & Faubion, W. A., Apr 7 2022, In: Frontiers in Pediatrics. 10, 874116.Research output: Contribution to journal › Article › peer-review
- Viral prevalence by gestational age and season in a large neonatal cord blood cohortSloan, P. E., Rodriguez, C. & Holtz, L. R., 2022, In: Journal of Maternal-Fetal and Neonatal Medicine. 35, 25, p. 8482-8487 6 p.Research output: Contribution to journal › Article › peer-review