We all have microbial communities in and on our bodies that are extremely important for health and development. From previous research, we know that these microbes are picked up very early in life and that they help babies digest food and develop healthy immune systems. We also know that an abnormal microbiome can be associated with increased risk for conditions like asthma, allergies, infections, and obesity.
The MOM study is a longitudinal, observational study that follows participating families for approximately one year to identify the origins of infants’ microbiomes and microbial transmission dynamics among household members and the environment. The central hypothesis of this study is that the term infant bacterial microbiome and virome are acquired from post-natal environmental exposures and persist throughout infancy.
We are creating a repository of both clinical data and biological samples of pediatric patients seen at St. Louis Children's Hospital with suspected and confirmed celiac disease. This repository will provide a rich resource to better understand the natural disease process and to ask questions regarding the many currently unanswered questions about celiac disease.